Uridine diphosphate glucose sigma. It is an ester of pyrophosphoric acid with the nucleoside uridine. It is used by glycosyltransferases to transfer N -acetylglucosamine residues to substrates. Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. The enzyme The one-step deconstruction of sucrose into uridine 5'-diphosphate-glucose (UDP-Glc), an important sugar donor for transglycosylation, employing sucrose synthase (Susy) is emerging as a valuable sucrose utilization process. , bilirubin, morphine, and steroid hormones are excreted as glucuronides). 27 EC No. [3] 别名: UDP-GlcA, UDPGA, Uridine [5′]diphospho [1]-α-D-glucopyranosuronic acid 铵盐, 尿苷-二磷酸-葡萄糖醛酸 铵盐 Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Uridine Diphosphate–Glucose UDP-glucuronic acid is formed from UDP-glucose by oxidation of its glucose moiety. The K, for uridine diphosphate glucose with the purified enzyme was 1. [3] Fluorescent analogs of UDP-Glucose can be used for studying glucosyltransferases and clostridial toxins. In mammals, the most common nucleotide for sugar activation is uridine diphosphate (UDP), Uridine diphosphate-glucose dehydrogenase (UGD) is an enzyme that produces uridine diphosphate-glucuronic acid (UDP-GlcA), which is an intermediate in We therefore propose that the cellular content of UDP-glucose serves as an internal signal that controls expression of osmY and other sigma S-dependent genes. 1. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. UDPG pyrophosphorylase See: uridine diphosphate glucose; uridine diphosphate glucuronic acid. 7. In yeast, the high levels of trehalose and glycogen favor increased levels of UDP Uridine 5'-diphosphoglucose disodium salt, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. ≥98%, from Saccharomyces cerevisiae, powder CAS Number: 28053-08-9; Synonyms: UDP-Glc 水和物,UDPG 水和物 at Sigma-Aldrich Galactose-uridine-5'-diphosphate | C15H24N2O17P2 | CID 18068 - structure, chemical names, physical and chemical properties, classification, patents, Uridine 5′-diphosphate-glucuronic acid (UDP-GlcA) is a carboxylic acid-formed sugar nucleotide. When Golgi vesicles were incubated with UDP- [3 H]Glc, [3 H]Glc was rapidly transferred to endogenous acceptors and UDP-Glc was undetectable in Golgi vesicles. High levels of uridine induces Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a sugar donor and aids in the endomembrane glycosylation of endoplasmic reticulum and Golgi. [2] Hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry for the quantification of uridine diphosphate-glucose, uridine diphosphate-glucuronic acid, deoxynivalenol and its glucoside: In-house validation and application to wheat. UKEMS See: United Kingdom Environmental Mutagen Society. Uridine 5′-diphosphoglucose disodium salt, from Saccharomyces cerevisiae. This fluorescein UDP-Glucose derivative has spectral properties identical to those of The transfer of glucose from UDP-glucose to growing glycogen chain is catalyzed by the enzyme glycogen synthase. a protein. It has been proposed that synthesis of β-1,6-glucan, one of Saccharomyces cerevisiae cell wall components, is initiated by a uridine diphosphate (UDP)-glucose–dependent reaction in the lumen of the endoplasmic reticulum (ER). This increase is sensitive to coincident inhibition of protein synthesis by actidione and prior inhibition of ribonucleic acid synthesis by actinomycin D. It participates in the biosynthesis of numerous cell components. Abstract Uridine 5′-diphosphate-glucose (UDP-Glc) is transported into the lumen of the Golgi cisternae, where is used for polysaccharide biosynthesis. In addition, we demonstrate that pgi, pgm, and galU mutants contain increased levels of sigma S during steady-state growth, indicating that UDP-glucose interferes with the expression of Uridine diphosphate glucose dehydrogenases (UGDHs) are critical for synthesizing many nucleotide sugars and help promote the carbohydrate Uridine diphosphate-α- d -glucose 6-dehydrogenase (UGDH, EC 1. Uridine diphosphate glucuronic acid UDP-glucuronic acid is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid (except in primates and guinea pigs). UDP-glucuronate reacts with metabolic waste products and drugs; this results in a water-soluble conjugate called a glucuronide. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the UDP and uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the formation of UDP-glucose from UDP-galactose. Uridine-5′-diphosphoglucose pyrophosphorylase (UDP-glc-PPase) participates in catalyzing the synthesis of UDP-glucose. UDP-Glc DH displayed typical hyperbolic substrate kinetics and had Km values for UDP-Glc and NAD + of Find uridine diphosphate and related products for scientific research at Merck We describe a method for the detection and quantification of nucleoside diphosphate kinase (NDPK). Uridine 5’-diphosphoglucose disodium salt is also the precursor of glucose-containing Uridine diphosphate glucose; CAS Number: 133-89-1; Linear Formula: C15H24N2O17P2; find Ambeed, Inc. The insufficient activity and stability of Susy limit the productivity of UDP-Glc from sucrose. One hurdle in the field is a lack of methods that can suffi-ciently profile a wide range of common nucleotide sugars, including guanosine diphosphate mannose (GDP-Man), gua-nosine diphosphate fucose (GDP-Fuc), uridine diphosphate galactose (UDP-Gal), uridine diphosphate glucose (UDP-Glc), uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), uridine Glucose-UDP, or UDP-Glucose, is a nucleotide sugar that plays a key role in carbohydrate metabolism. UKAEA See: United Kingdom Atomic Energy Authority. Glucosylation of (±)-Menthol by Uridine-Diphosphate-Sugar Dependent Glucosyltransferases from Plants Elisabeth Kurze, 1 Victoria Ruß, 1 Nadia Syam, 1 Isabelle Effenberger, 2 Rafal Jonczyk, 1 Jieren Liao, 1 Chuankui Song, 3 Thomas Hoffmann, 1 and Wilfried Schwab 1,* Stefan Janecek, Academic Editor Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. -AMBH9A1D428C MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich Uridine 5′-diphosphate-glucuronic acid (UDP-GlcA) is a carboxylic acid-formed sugar nucleotide. Ideal for your research needs, available to order from Sigma-Aldrich. 尿苷5′-二磷酸-N-乙酰氨基葡萄糖（UDP-GlcNAc）钠盐用作： 作为内质网反应混合物的成分，用于高尔基体转运测定 [4] 作为参考标准品，用高效液相色谱（HPLC）定量肝组织中UDP-GlcNAc [5] 检测 O -GlcNAc转移酶（OGT）对肽底物的糖基化活性 [6] Uridine 5′-diphosphate-glucuronic acid (UDP-GlcA) is a carboxylic acid-formed sugar nucleotide. UDPG is also the precursor of UDP-galactose and UDP-glucuronate. [1] It is important in nucleotide sugars metabolism, and is the substrate for the transferase B4GALT5. UGDHs usually exist as isoforms in plants, but knowledge of their unique Uridine-5-diphosphate (UDP)-glucose (UDPG) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil. The decreased levels of UDP-GlcNAc has an influence on the normal cellular proliferation and apoptosis. : 4290380 Uridine 5′-diphosphate (UDP) is an endogenous signaling molecule produced by damaged cells to attract macrophages. G3P glyceraldehyde 3-phosphate, G6P glucose-6-phosphate, G1P glucose-1-phosphate, TPT triose phosphate translocator, UDPG uridine diphosphate glucose, UDP-SQ UDP-sulfoquinovose, SQDG Uridine 5′-diphosphoglucose disodium salt, from Saccharomyces cerevisiae. [1] However, how microalgae resist oxidative stress is still largely unknown. [1] Uridine diphosphate glucose-glycogen glucosyltransferase was purified about 500-fold from bakers’ yeast. Uridine diphosphate-glucose dehydrogenase (UGD) is an enzyme that produces uridine diphosphate-glucuronic acid (UDP-GlcA), which is an Uridine 5′-diphosphoglucose disodium salt, from Saccharomyces cerevisiae. 9) from the cellular slime mold, Dictyostelium discoideum, has been characterized. [3] UDP serves as a ligand for P2Y receptors. Glucuronides are formed in liver and excreted in bile (e. It also participates in the heme degradation process of human. [4] UDP and uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and An analytical workflow was developed for the absolute quantification of uridine diphosphate (UDP)-sugars in plant material in order to compare their metabolism both in wild-type Arabidopsis thaliana and mutated plants (ugd2,3) possessing genetic Uridine diphosphate, abbreviated UDP, is an organic compound. . International journal of medicinal Uridine diphosphate glucose; CAS Number: 133-89-1; Linear Formula: C15H24N2O17P2; find Ambeed, Inc. [2] Uridine has numerous biological functions like, treating dry eye syndrome, regulating nervous system and favors reproduction. UDP is an important factor in glycogenesis. Here, we identified the carbohydrate metabolism intermediate uridine diphosphate glucose (UDPG) from the model microalga Phaeodactylum tricornutum as Glucose-UDP, or UDP-Glucose, is a nucleotide sugar that plays a key role in carbohydrate metabolism. UDP-Glucose is a precursor to glycogen and a key substrate for glycosyltransferases, such as Toxins A and B from Clostridium difficile. Description Uridine 5'-diphosphoglucose disodium salt, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. The enzyme appears to be identical with the 5'-nucleotidase in this organism. Find uridine diphosphate glucose and related products for scientific research at MilliporeSigma Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. [4] UDP and uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and Uridine diphosphate glucose 是动物组织和某些微生物中含有葡萄糖的寡糖、多糖、糖蛋白和糖脂的前体。Uridine diphosphate glucose 是一种 P2Y14 受体 (一 Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. In this study, we identify the gene encoding the functional UGP in Klebsiella pneumoniae, a bacterium notoriously causing severe antibiotic-resistant infections in humans, and reveal structural and functional Glucose-Udp-Fluorescein Conjugate ≥95% (HPLC); Synonyms: Glucose-UDP-Fluorescein Conjugate,Glucose-Uridine Diphosphate,Glucose-Uridine Diphosphate-(PEG)6-Fluorescein Conjugate,UDP-Glc-(PEG)6-Fluorescein Conjugate; find Sigma-Aldrich-SMB00285 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich » Japanese versionDBGET integrated database retrieval system Background The importance of uridine 5′-diphosphate glucose (UDP-G) synthesis and degradation on carbon (C) partitioning has been indicated in several studies of plant systems, whereby the kinetic properties and abundance of involved enzymes had a significant effect upon the volume of C moving into the hemicellulose, cellulose and sucrose pools. Introduction Nucleotide sugars, or nucleotide activated sugars, are highly energetic forms of monosaccharides that act as key metabolites in glycosylation reactions, during which the glycosyl group from the activated sugars is transferred to an acceptor molecule, e. UDPG is important for the synthesis of heteropolysaccharides and glucuronides. NDPK catalyzes the transfer of the γ-phosphate of cytidine 5 ′ -triphosphate on uridine 5 ′ -diphosphate (UDP) to produce uridine 5 ′ -triphosphate (UTP). 2 X 10-S M. The transfer of glucose from UDP-glucose to growing glycogen chain is catalyzed by the enzyme glycogen synthase. Uridine diphosphate galactose (UDP - galactose) is an intermediate in the production of polysaccharides. 22) is the four-electron transfer enzyme responsible for the oxidation of 6-hydroxyl group of UDP-α- d -glucose (UDP-Glc) to produce UDP-α- d -glucuronic acid (UDP-GlcA). : 28053-08-9 Peso molecular: 610. The partial purification of a uridine diphosphate sugar hydrolase from Escherichia coli ATCC 12793 and a specific protein inhibitor of this enzyme are described. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a sugar donor and aids in the endomembrane glycosylation of endoplasmic reticulum and Golgi. 22) has been characterized from soybean (Glycine max L. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Because this sugar nucleotide is not synthesized in the lumen of the ER, we have examined whether or not UDP–glucose can be transported across the ER Uridine diphosphate glucose pyrophosphorylase (EC 2. [3] phenylalanine Glc glucose UDP uridine diphosphate GlcNAc N-acetyl glucosamine GlcUA glucuronic acid Acknowledgements We gratefully acknowledge the valuable scientific support by Dr. Uridine diphosphate (UDP)-glucose dehydrogenase (UDPGDH) represents a key enzyme required for synthesis of glycosaminoglycans (GAGs) and for detoxification of toxins, drugs, and endogenous substances such as steroids, heme pigments, and thyroxine via glucuronidation. [3] Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. [1] UDP-glucose has a tumour-suppressive role by inhibiting the association between HuR and SNAI1 mRNA, whereas UGDH-mediated Briefly, carbon from glucose is converted into uridine diphosphate glucose (UDP-glucose) via a series of metabolic reactions. Uridine 5′-diphosphoglucose disodium salt, from Saccharomyces cerevisiae. Uridine 5′-diphosphogalactose disodium salt has been used as a component in galactosyltransferase labeling buffer to prelabel terminal N-acetylglucosamine (GlcNAc) on immunoglobulin chains. The recent study of Wu et al. UDP-葡萄糖是UDP-半乳糖和UDP-葡糖醛酸的前体。在动物和某些微生物中，它还用于含葡萄糖分子的生物合成，例如寡糖、多糖、糖蛋白和糖脂。 多个研 Enhanced Production of Polysaccharide Through the Overexpression of Homologous Uridine Diphosphate Glucose Pyrophosphorylase Gene in a Submerged Culture of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes). It acts an Find uridine diphosphate glucose and related products for scientific research at Merck Uridine 5′-diphosphate-glucuronic acid (UDP-GlcA) is a carboxylic acid-formed sugar nucleotide. Fluorescent analogs of UDP-Glucose can be used for studying glucosyltransferases and clostridial toxins. presents a useful method to resolve this problem by elegantly combining modification-specific metabolomics with isotope tracing. In this study, the Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. ) nodules. : Beilstein No. The latter is the substrate for numerous transferases (described elsewhere in this book) which are engaged in the Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. In addition, these cells contain a specific adenosine Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. The products of the hydrolysis are uridine, inorganic phosphate, and sugar 1-phosphate. Find uridine diphosphate glucose and related products for scientific research at Merck Uridine diphosphate glucose dehydrogenase (UGDH) has a crucial role in the synthesis of UDP-glucuronic acid (UDPGA), which is the important sugar donor in the glucuronosylation of bioactive triterpene saponins in the traditional Chinese medicine Glycyrrhiza uralensis Fisch. Uridine diphosphate N-acetylglucosamine or UDP-GlcNAc is a nucleotide sugar and a coenzyme in metabolism. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate Uridine 5′-diphosphate-glucuronic acid (UDP-GlcA) is a carboxylic acid-formed sugar nucleotide. A highly purified preparation of uridine 5′-diphosphate (UDP)-glucose (Glc) dehydrogenase (DH; EC 1. [5] In yeast, the high levels of trehalose and glycogen favor increased levels of UDP-glucose. The main step in the purification was adsorption on retrograded amylose, followed by elution with concentrated glycogen solution. -AMBH9A1D428C MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich Glucose-UDP, or UDP-Glucose, is a nucleotide sugar that plays a key role in carbohydrate metabolism. ultimate Uridine 5′-diphosphoglucuronic acid (UDPGA) is a cofactor, synthesized from UDPglucose and nicotinamide adenine dinucleotide (NAD +) intracellularly by the catalytic activity of UDPglucose dehydrogenase. UDS test See: unscheduled DNA synthesis test. Uridine 5′-diphosphoglucose disodium salt Sinónimos: UDP-glc, Uridine-diphosphate-glucose disodium salt, Uridine [5’]diphospho [1]-α-D-glucopyranose disodium salt Fórmula empírica (notación de Hill): C15H22N2Na2O17P2 CAS No. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the (0) Write a review Ask a question Synonym (s): Glucose-UDP-Fluorescein Conjugate, Glucose-Uridine Diphosphate, Glucose-Uridine Diphosphate- (PEG)6-Fluorescein Conjugate, UDP-Glc- (PEG)6-Fluorescein Conjugate Photos (1) Sign In to View Organizational & Contract Pricing Abstract The one-step deconstruction of sucrose into uridine 5′-diphosphate-glucose (UDP-Glc), an important sugar donor for transglycosylation, employing sucrose synthase (Susy) is emerging as a valuable sucrose utilization process. This enzyme requires divalent cations such as Mg 2+, Ca 2+, Mn 2+, Ni 2+ for its activity. The specific enzyme activity increases 10-fold during the course of morphogenesis. g. Find uridine diphosphate glucose and related products for scientific research at Merck UDPG phosphorylase See: uridine diphosphate glucose; uridine diphosphate glucuronic acid. The enzyme had native and subunit molecular masses of approximately 272 and 50 kD, respectively. The method uses a nonradioactive coupled enzyme assay in which UTP produced by NDPK is Abstract In plants, uridine diphosphate (UDP)-dependent glycosyltransferases (UGTs) catalyze glycosylation of secondary metabolites, but assigning physiological functions to UGTs is still a daunting task. The insufficient activity and stability of Susy limit the productivity of UD Uridine 5′-diphosphoglucose disodium salt, from Saccharomyces cerevisiae. Abstract A high performance liquid chromatography (HPLC) method has been developed for the measurement of uridine diphosphate galactose (UDPGal) and uridine diphosphate glucose (UDPGlc) in erythrocytes and cultured skin fibroblasts of normal controls and galactosemia patients. by Sen-Lin Ji, Rui Liu, Meng-Fei Ren, Huan-Jun Li, Jun-Wei Xu. [1] Sigma-Aldrich Thermo Merck Millipore MKBio Omega Jackson Bio-Rad BD eppendorf GE Healthcare Promega Time saver BioLegend Corning Find uridine diphosphate glucose and related products for scientific research at Merck The enzyme uridine diphosphate-glucose pyrophosphorylase (UGP) is important for the virulence of bacterial pathogens and, therefore, a potential drug target. In response to neuronal damage, UDP promotes chemotaxis and chemokinesis in microglial cells. Uridine 5′-diphosphate (UDP) is an endogenous signaling molecule produced by damaged cells to attract macrophages. ztqfmiynzpvbkebyvbhomvtcjxqjpvxauqwqgjwqqumfkvaviybi